T2EVOLVE is a new breakthrough alliance of academic and industry leaders in cancer immunotherapy under the European Union’s Innovative Medicines Initiative (IMI). The key objective of T2EVOLVE is to accelerate development and increase awareness and access of cancer patients to immunotherapy with immune cells that harbor a genetically engineered T-cell receptor (TCR) or synthetic chimeric antigen receptor (CAR). Simultaneously, T2EVOLVE aims to provide guidance on sustainable integration of these treatment into the EU healthcare system.
This project receives funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 945393. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation program and EFPIA.
CAR T-cell therapy
Engineered T-cell therapy is a revolutionary cancer treatment where a patient’s immune cells are reprogrammed to seek and destroy cancer cells. This transformative treatment has the potential to cure cancer with a single shot. This therapy is approved and available in the EU for the treatment of leukemia and has the potential to become a blockbuster therapy for other types of cancer, as well as infectious diseases and autoimmune diseases in the future.
For additional information on CAR T-cell technology please contact UKW.
The T2EVOLVE consortium is excited to kick-off the new EU project T2EVOLVE virtually (January 19, 2021). Together with its IMI officer KARROUM Oussama, the consortium intensively discussed the new, promising CAR T- cell therapy vision and approach in Europe.
Coordinators Team
Univ.Prof.Dr.med. Michael Hudecek
Director CAR-T Research Program, Cellular Immunotherapy for Malignant Diseases Max Eder Research Group‚ CAR T-cell engineering, Universitätsklinikum Würzburg, Germany
Dr. Hélène Negre
CMC Project leader for the allogenic CAR-T program at SERVIER IRIS and EPFIA project leader T2Evolve, Suresnes Cedex, France
